The best Side of cees dekker
The best Side of cees dekker
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Human Rad51 filaments on double- and one-stranded DNA: correlating typical and irregular sorts with recombination perform.
[Laughs] ‘It had been absolutely a fantastic possibility! At some time, I had been very well informed that it could go Erroneous and that I could grow to be much less effective, but I just ignored that. Curiosity has normally been my strongest driving drive. And by chance it all worked out.’
Deposition and atomic force microscopy of person phthalocyanine polymers among nanofabricated electrodes
2010, formulated a completely new way (‘wedging transfer’) to manipulate nanostructures; initial report of DNA translocation by means of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into good-state nanopores
Our investigation ranges with the biophysics of DNA to artificial cells and outside of. You should take a look under with the spectrum of our recent assignments.
All parameters were precisely the same for every panel With this video clip, apart from the First placement of your 6hb rod (revealed in blue) within the nanopore. Simulations that terminated early resulting from translocation of the rod through the pore are marked by a grey background.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, in addition to a 3D rendering on the movement in the DNA rod is exhibited.
‘Certainly, I realize people today had been amazed at the time. At the end of the nineties, After i was in my forties, I was Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t study A lot any more. The sector went extra into the application aspect, how you could potentially integrate nanotubes into electronic circuits.
Resolving the stage measurement in condensin-driven DNA loop extrusion identifies ATP binding because the step-generating process
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2001, discovery of single-electron transistors at room temperature according to nanotubes; realization of initial logic circuits with carbon nanotube gadgets; and discovery on the molecular framework of DNA mend enzymes with AFM
Developments in nanotechnology from the nineteen nineties built setting up Digital equipment from one molecules a risk. Cees Dekker recounts how his workforce established a room-temperature transistor based on just one carbon nanotube.
2004, discovery of latest physics in translocation of DNA via nanopores; first experimental review of ions conduction in nanofluidic channels; very first electrochemistry ceesdekker with individual solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; very first biophysics characterization of the mechanical Houses of double-stranded RNA; and very first one-molecule examine of DNA translocation by a restriction-modification enzyme.